The Duke Endowment enriches lives and strengthens communities in North Carolina and South Carolina.

We support grantees as they nurture children, promote health, educate minds and uplift spirits

Child family well being

Child & Family Well-Being

All children deserve to grow up safe from maltreatment, supported by nurturing families and caring adults. The Duke Endowment is dedicated to enabling children in the Carolinas to live successful lives.

Health care

Health Care

The Duke Endowment believes that maintaining good health over time is dependent on a person’s ability to lead a healthy lifestyle and access essential health care services.

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Higher Education

The Duke Endowment supports the four institutions named in Mr. Duke’s Indenture of Trust: Davidson College, Duke University, Furman University and Johnson C. Smith University.

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Rural Church

We are committed to preserving the pivotal role churches play in rural communities. The Duke Endowment supports clergy and congregations — ensuring they have the tools they need to walk faithfully together — as they strengthen rural areas.

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Additional Focus

Through other Endowment initiatives, and particularly our strategic emphasis on early childhood, we respond to today’s needs and intervene early to keep tomorrow’s problems from taking root.

Our Renewed Grantmaking Strategies

We have just completed an intensive effort to renew the strategic approaches behind our grantmaking in each of our four program areas. President Rhett Mabry shares reflections and insights coming out of the process as we prepare for the journey ahead.

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Our Commitment to Racial Equity, Diversity and Inclusion

We are systematically reviewing our grantmaking and organizational culture through the lens of racial equity, diversity and inclusion to better understand and fight the damaging effects of historic inequities and systemic bias across our work.

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Our Strategic Focus on Ages Zero to Eight 

We believe that a good beginning for children bodes well for their lives as adults and for their communities. The Endowment seeks strong starts for more children.

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Latest News & Stories

Get the latest from the Endowment and read more about the impact of the work being done by our grantees and individuals in the field

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S.C. Medical School Showcases Grant-Funded Initiative for Pregnant Moms

An Endowment grant is helping the Medical University of South Carolina develop a life-saving on-demand mental health resource for new moms and moms-to-be.

August 16, 2022 | Medical University of South Carolina

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Alliance for a Healthier South Carolina Receives $1.2 Million Grant to Improve Community Health

A three-year, $1.2 million grant from The Duke Endowment will help the Alliance for a Healthier SC develop a sustainable statewide infrastructure to help hospitals and community partners impact complex health and social issues more effectively.

August 11, 2022 | News 19 WLTX

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Conway Medical Center receives $510K grant to help expand telehealth

A grant from The Duke Endowment will soon allow Conway Medical Center to help those who don’t live near a doctor or don’t have the means to get to appointments.

July 21, 2022 | WMBF News

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Vanderbilt, UNC and Duke Nurse-Midwives Join Forces to Reduce Black Maternal Health Risks

Nurse-midwives and educators from three prominent research universities have teamed up to improve pregnancy outcomes in Black communities by providing specialized training for doulas, persons who support birthing mothers and families through the entire process of childbirth.

June 28, 2022 | VUSN Communications

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A Leap Forward for the Arts at Duke with $7 Million Award from The Duke Endowment

The Duke Endowment has awarded Duke University $7 million to support the arts, including funds for a new exchange program with music institutions like the New England Conservatory (NEC) and the Curtis Institute and a deeper investment in the arts in the Durham community.

June 9, 2022 | Giving.Duke.EDU

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S.C. Children's Trust Launches Video Series Promoting the Positive Parenting Program

Children's Trust has launched the first interview in a new series highlighting practitioners in South Carolina who deliver the Positive Parenting Program (Triple P).

June 2, 2022 | S.C. Children's Trust

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Apply for a grant

Select 501(c)(3) organizations in North Carolina and South Carolina may be eligible for grants through The Duke Endowment.

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Or Edit an Existing Application