Health Care

The Duke Endowment believes that all people can achieve their best health when communities are designed to support healthy lifestyles and when our health care system is able to engage patients and provide holistic care that meets the unique needs of each individual.

Challenge

The U.S. spends more on health care per capita than any other country but does not achieve better outcomes in terms of life expectancy, health status or patient satisfaction. Our health care system is designed to provide excellent medical care to the sick. However, it is often limited in its ability to take a comprehensive approach to preventing illness and supporting wellness and provide equal opportunities for health and well-being to all segments of the population. These limitations can contribute to disparities in health status and health care utilization based on a range of social factors. 

Our Objective

We seek to improve health status and reduce health disparities in the Carolinas by ensuring all people can access timely and appropriate health care, lead a healthy lifestyle, and have their basic social needs met. 

What We Fund

Improving health and reducing health disparities will require communities and the health care system to innovate and expand access to care for underserved populations. We look for opportunities to support the development and testing of new approaches that can outperform the current standard of care. These new approaches will require robust evaluation plans that can build the evidence necessary to understand what works and accelerate the systemic reforms necessary to scale and sustain best practices.

Our founder’s keen interest in innovation drives us to consider new ways to optimize person-centered and community-based approaches to improving health. The majority of grants will follow one of our two strategies. 

Strategies

HC Strategy updates 2026 JAN29 Build Community Coalitions

Build Community Coalitions

We build coalitions that bring together health systems, public health agencies and community-based organizations to advance programs and policies that promote healthy lifestyles.

HC Strategy updates 2026 JAN28 Advance Innovation

Advance Innovation

We partner with health systems and community-based organizations to identify, develop and test innovative programs that have the potential for long-term scale and sustainability. 

Apply for a Grant

Select 501(c)(3) organizations in North Carolina and South Carolina may be eligible to receive funding.

  • The Health Care program area uses a short pre‑application to confirm eligibility and project fit. 
  • Pre-application deadlines are May 15 and November 15.
  • The portal opens approximately six weeks before each deadline and is only available during that time. Pre-applications are reviewed on a rolling basis up until the deadline. 
  • After review of the pre-application, applicants will either be:
    • Invited to submit a full application, or
    • Notified that the project does not align with current priorities
  • Full application deadlines are June 15 and December 15
  • To begin the application process, please click on ​“Start a New Application” below

Before You Proceed

The Duke Endowment’s grant application and reporting process is powered by Blackbaud. If your organization currently uses Blackbaud, please use your existing login credentials to access the grantee portal. If your organization does not have a current Blackbaud ID, please select ​“create account” when prompted to login. For a step-by-step process click here.

You can access all previous and in-progress applications through the grantee portal.

Funding Priorities

School-Based Mental Health

The Health Care program area seeks to support the mental well-being of children through school-based programs and evidence-informed systems of care.

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Population Health

The Health Care program area is building capacity at the state, regional, and local level to link government, health, and social service providers so that all Carolinians have the opportunity to lead a healthy lifestyle and address their social needs.

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Workforce

The Health Care program area seeks to support the work of health systems across the Carolinas through the recruitment of the future healthcare workforce and retention of the current workforce.

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Health for Individuals with Complex Care Needs

The Health Care program area seeks to improve health outcomes and decrease the total cost of care for individuals with complex care needs by providing them with comprehensive and individualized care.

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Access to Care for Underserved Populations

The Health Care program area seeks to reduce health disparities and improve clinical outcomes by increasing access to essential services for underserved and rural populations.

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Maternal & Infant Health

The Health Care program area seeks to improve maternal and infant health outcomes and reduce health disparities.

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